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Agrochemicals Developed In-house

Research Achievements

We are engaged in research and development to create safe and effective agrochemicals by recognizing that agrochemicals are indispensable to food security and stability in the world.

Our laboratories are working cohesively to discover and develop new agrochemicals: the Chemical Science Laboratory explores new agrochemicals, the Bioscience Research Laboratory accelerates the pipeline development of agrochemicals and expands the applications of existing agrochemicals, Process Development Laboratory studies the manufacturing process of agrochemicals, the Formulation Research Laboratory investigates formulations that maximize agrochemical performance, and the Safety Science Research Laboratory assesses the initial safety of agrochemicals.

Regarding the discovery of new agrochemicals, we have persistently discovered innovative agrochemicals using computer-assisted drug design, bioscientific and molecular biological approaches in addition to our organic synthetic methods have been acknowledged for the synthesis of trifluoromethylpyridine derivatives.

To develop our newly discovered agrochemicals at the global level, our Safety Science Research Laboratory plays a leading role in helping their speedy approval in each country through safety assessment and environmental science research. These efforts have successfully led to the development, approval, commercialization, and marketing of many agrochemicals worldwide.

Herbicide for paddy fields

Pyrazoxyfen, PAICER, 1985, 3 countries

Used as a base agent for ONEBEST, ONEALL, and TOBIKIRIJUMBO, pyrazoxyfen helps inhibit weed growth in wide areas for a long time period, thus streamlining field work.

Herbicides for upland farming, fruit cultivation, and turf growing

Fluazifop-P-butyl, ONESIDEP, 1986, 20 countries

Strongly active for a wide variety of grassy weeds ranging from annuals to perennials, Fluazifop-P-butyl has been used worldwide in farms growing soybeans, cottons, beets, and other broadleaf crops.

Flazasulfuron, SHIBAGEN, 1989, 35 countries

As a sulfonylurea herbicide, flazasulfuron is used at very low dose and provides long-term herbicidal effects on a wide variety of weeds in orchards, warm-season turf, and non-crop areas.

Nicosulfuron, ONEHOPE, 1994, 58 countries

Nicosulfuron is a sulfonylurea herbicide which is exclusively used for maize. It acts on grassy and broadleaf weeds at the same time. Its performance has been acknowledged in major worldwide markets including Europe, Central and South America, and Japan.

Insecticides/Nematicides

Chlorfluazuron, ATABRON, 1988, 34 countries

Chlorfluazuron is one of our groundbreaking insect growth regulators. It inhibits the biosynthesis of chitin, a material contained in the outer skin of insects. It has strong insecticidal activity against lepidopteran, thysanopteran, and hemipteran larvae.

Fosthiazate, NEMATHORIN, 1992, 36 countries

Fosthiazate is a low-toxicity organophosphorous insecticide. Low concentration levels of this non-fumigating agent are effective against all nematode development stages. Because fosthiazate is systemic in plants, its soil application acts on ground pests like spider mites, Thrips palm Karnyi, and greenhouse whiteflies.

Flonicamid, ULALA, 2003, 32 countries

Flonicamid is an insecticide that enables integrated pest management (IPM) because it exhibits low activity against natural enemies and insect pollinators. It is highly active against sup-sucking Hemiptera and Thysanoptera bugs, especially aphids. Its unique action inhibits sup sucking, thus providing the insecticidal effect. Flonicamid also acts on resistant strains, because its mode of action differs from previous insecticides.

Fungicides

Fluazinam, FROWNCIDE, 1990, 58 countries

Fluazinam is a protective pyridinamine fungicide that acts on a broad spectrum of fungi. It is effective against diseases that have become resistant to other agents. It is also active against diseases that are difficult to control like the root rot of fruit trees and the bacteria gall of Brassicaceae vegetable roots. It is recognized as a mitecide for controlling potato late blight in Europe and Japan.

Cyazofamid, RANMAN, 2001, 55 countries

With a phenylimidazole skeleton, cyazofamid is high selective and effective against Oomycetes which cause downy mildew and late blight, and Plasmodiophoromycetes which induce bacteria gall of Brassicaceae vegetable roots). Its novel mode of action consists in inhibiting the Qi site of mitochondrial complex III in the intramitochondrial electron transport system.

Biological insecticides

We help the development of environmentally conservative agrochemical practices that use natural enemies like Phytoseiulus persimilis Athias-Henriot, Encarsia formosa Gaha, Aphidius colemani Viereck, and Diglyphus isaea against spider mites, greenhouse whiteflies, aphids, and leaf miners.

Achievement Award from the Pesticide Science Society of Japan

-	1987:	Development of the Fluazifop herbicide
-	1992:	Development of the Chlorfluazuron insect growth regulator
-	1998:	Development of the Fosthiazate insecticide/nematicide
-	2000:	Development of the Nicosulfuron herbicide
-	2004:	Development of the Cyazofamid fungicide

Okochi Memorial Technology Prize

1989:

Development of industrial manufacturing methods for 2-chloro-5-trifluoromethylpyridine—a valuable intermediate for a bioactive substance

Minister of Japanese Agriculture, Forestry and Fisheries Prize

1993:

Introduction and granulation of 2,4-D
(2,4-D Industry-government-academia Research Group)