Globally Trusted
Titanium Dioxide for Cosmetics
From pigments to fine particle sizes
Wide lineup
PURPOSE Contributing to the creation of beauty through the development of reliable materials
For makeup and sunscreen applications, factors such as raw material purity, quality control, and particle design are important criteria for product selection and formulation design. We manufacture titanium dioxide for cosmetics based on these factors as our technological foundation.
ISK's Strengths
High-Purity Refining Technology
Proprietary refining technology delivers high-purity titanium dioxide with low impurity and heavy metal levels.
Regulatory-Compliant
Quality Control
A quality control system that meets or exceeds cosmetic regulatory standards in each country.
Particle Control Technology
Particle control technology enables products tailored for transparency, dispersibility, and sensory feel.
Based on these technologies, we can select products according to the intended use and desired characteristics, and can handle a wide range of cosmetic formulations, from makeup to sunscreen.
Furthermore, by providing a stable supply of high-purity, high-quality raw materials, we hope to contribute to ensuring safety and security in the cosmetics industry and the development of beauty.
Product features
Pigment-grade titanium dioxide
This pigment combines high whiteness with excellent hiding power, making it suitable for foundation applications.
Recommended brand: Tipaque® CR-50

Global Distribution
Tipaque® CR-50 is sold globally as titanium dioxide for cosmetics.
High hiding power
It has high whiteness and excellent hiding power, making it suitable for use in foundations and other applications.
Formulation Stability
Surface treatment suppresses photoactivity, allowing formulations with stable quality.
Good dispersibility
The surface treatment makes it easy to disperse.
Color and hiding power comparison color sample
- CR-50 has an average particle size of 250 nm designed to ensure efficient light scattering, and is characterized by high whiteness and excellent hiding power.
- By changing the particle size, it is possible to adjust the color tone and hiding power. PFC415 has a smaller particle size than CR-50, which reduces the hiding power and gives it a bluish color tone.
Ultrafine titanium dioxide
This is titanium dioxide with smaller particle size compared to pigment-grade titanium dioxide.
By controlling the particle size, transparency is improved and UV rays are efficiently blocked, making it suitable for sunscreens and UV care cosmetics.
Recommended brands: MPT-186, MPT-187
Transparency that supports a natural finish
The smaller the particle size, the higher the transparency, contributing to a natural finish with less white cast.
Wide-range UV protection
It blocks a wide range of UVB/UVA rays to protect your skin from UV rays.
Suitable for concealers and BB creams
Mild coverage
Particle sizes between 60nm and 100nm add a slight tint, making them suitable for applications requiring mild (moderate) hiding power, such as concealers and BB creams.
Formulation Stability
Surface treatment suppresses photoactivity, allowing formulations with stable quality.
Good dispersibility
The surface treatment makes it easy to disperse.
UV protection and transparency
- UV protection effect: Small particle size provides excellent UVB blocking, while large particle size provides broad UVA to UVB blocking.
- Transparency: The smaller the particles, the better the transparency.
Product List
Click on the product name to view product details.
*under development
| Ultrafine titanium dioxide | Pigment-grade titanium dioxide | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| surface treatment | Primary particle diameter (short axis) | Primary particle size | ||||||||
| 10nm | 15nm | 20nm | 30nm | 40nm | 60nm | 80nm | 100nm | 160nm | 250nm | |
| Al (OH)3 | TTO-V-5 | MPT-187 | TTO-51(A) | TTO-55(A) | TTO-80(A) | MPT-141 | CR-50 | |||
| SiO2 | MPT-192 | |||||||||
| Al (OH)3/ stearic acid |
TTO-V-4 | MPT-136 MPT-186 |
TTO-51(C) | TTO-55(C) | MPT-142 | |||||
| None | TTO-55(N) | *PFC415 | ||||||||

For product details and prescription compatibility,
Please feel free to contact us for more information.
To request an SDS download or sample,
Please proceed from here.
Regulatory Compliance List
Ultrafine titanium dioxide particles (main use: sunscreen)
| Product name | Regulatory Compliance | Quality and safety standards | ||
|---|---|---|---|---|
| NMPA | SCCS* | USP (attenuation grade) |
JSQI | |
| TTO-51 (A) | 〇 | 〇 | 〇 | 〇 |
| TTO-51 (C) | 〇 | 〇 | 〇 | 〇 |
| TTO-55 (A) | 〇 | 〇 | 〇 | 〇 |
| TTO-55 (C) | 〇 | 〇 | 〇 | 〇 |
| TTO-55 (N) | 〇 | N/A** | 〇 | 〇 |
| TTO-80 (A) | 〇 | 〇 | 〇 | 〇 |
| TTO-V-4 | 〇 | 〇 | 〇 | 〇 |
| TTO-V-5 | 〇 | × | 〇 | 〇 |
| MPT-136 | 〇 | 〇 | 〇 | 〇 |
| MPT-141 | 〇 | 〇 | 〇 | 〇 |
| MPT-142 | 〇 | 〇 | 〇 | 〇 |
| MPT-186 | 〇 | 〇 | 〇 | 〇 |
| MPT-187 | 〇 | × | 〇 | 〇 |
| MPT-192 | ー | 〇 | 〇 | 〇 |
* Regulation (EC) No 2019/1857, Annex VI, reference No.27a, Titanium Dioxide (nano)
** non-coated titanium dioxide
Pigment-grade titanium dioxide (main use: makeup)
| Product name | Regulatory Compliance | Quality and safety standards | ||
|---|---|---|---|---|
| NMPA | E-171 | CFR | JSQI | |
| CR-50 | 〇 | 〇 | 〇 | 〇 |
| *PFC415 | 〇 | 〇 | 〇 | 〇 |
* under development
ISK Titanium Dioxide
Story
ISK — Japan’s only titanium dioxide producer using a low-impact chloride process
Of the two main methods for manufacturing titanium dioxide, the chlorine method requires advanced technology. Ishihara Sangyo Kaisha is the only company in Japan that uses the chlorine method in addition to the conventional sulfuric acid method.
The chlorine method manufacturing process includes a purification step to remove impurities, making it possible to minimize the heavy metal content of titanium dioxide.In addition, because high-quality ore is used as the raw material, impurities are kept to a minimum, and this manufacturing method reduces the amount of industrial waste generated.
Market share backed by a long history
We began producing titanium dioxide using the sulfuric acid method in 1954, and in 1974 we became the first in Japan to commercialize the chlorine method.
With environmental concerns as a backdrop, we decided to adopt the chlorine method early on, and have continued to contribute to society through our titanium dioxide manufacturing business for over 70 years.

Titanium dioxide
Production Capacity
DomesticNo.1

Domestic market share
approx 1/3
A leading position
in Japan’s titanium dioxide market